How To Take Kudzu For Alcoholism?
Admittedly, the magnitude of the change in plasma ethanol levels in the present study is modest and may not be biologically significant, in spite of the observed statistical significance. We are currently engaged in studies employing proton magnetic resonance spectroscopy (MRS) to directly measure whether kudzu extract alters the rate and concentration of alcohol that actually enters the human brain. Studies such as this will likely yield more information on how kudzu extract reduces alcohol consumption. Subjective and psychomotor effects observed after alcohol consumption are typically attributed to be the direct effects of kudzu and alcohol alcohol on the CNS. There are data to suggest that many of these effects may be due, at least in part, to the primary alcohol metabolite, acetaldehyde (Kim et al., 2009). Daidzin has been shown to inhibit hamster and rat mitochondrial aldehyde dehydrogenase (ALDH-2) in vitro and is a mixed inhibitor of the human enzyme (Keung et al., 1997).
Kudzu to Stop Drinking Urges—How Does It Work?
«The fact that participants experienced a rapid rise in blood alcohol levels when pre-treated with kudzu has no apparent explanation and therefore requires additional research,» said Penetar. For the researchers, the next step is to determine if kudzu alters regional brain blood flow using an fMRI. The researchers observed 12 men and women in a double-blind placebo-controlled study. The participants were either treated with kudzu or a placebo for nine days, and then received a medium or high alcohol challenge to determine how prominently they presented alcohol-related symptoms. A prior study of kudzu to treat alcohol use in an outpatient setting reported that kudzu had no effect on maintaining sobriety or altering alcohol craving (Shebek and Rindone, 2000).
What to Know Before You Take Herbal Supplements
Today, the most popular ways to use kudzu root are as an herbal supplement or a root tea. More recently, kudzu root has made its way to Western countries as an herbal supplement. Until the effects of kudzu can be quantified properly in a larger study, then, and a standardised product is available on the market with the THR mark, it’s not something we can recommend you take.
Get Help for Alcoholism Today
While scientists need to do more research on the health effects of kudzu, some studies suggest that kudzu root may have other health benefits worth considering. For over 2,000 years, people have used kudzu root in traditional Chinese medicine for purposes like treating fevers, diarrhea, and even diabetes and heart disease (1). Lukas and Lee hold a patent for kudzu extract to treat alcohol abuse and dependence. McLean Hospital has licensed the production of kudzu extract (NPI-031) to Natural Pharmacia International (NPI), Inc. that markets it as Alkontrol-Herbal™. Kudzu for alcohol cravings is just one approach to reducing your intake, but addiction is a complicated psychological disease that requires a more comprehensive treatment plan.
- If I had been committed to using it to wean off of alcohol and then quit, it might have been a very valuable part of my recovery.
- As drinking behavior was measured using a wrist actigraphy device, we were able to monitor alcohol consumption continuously, 24 hours a day and seven days a week.
- Alcohol cravings are influenced by a combination of factors, which are often physiological, psychological and environmental.
- Additionally, kudzu may help reduce inflammation, which is often a contributing factor to the development of type 2 diabetes.
Sporadic missing data from the actiwatches were filled in from the back up daily diary data. Missing data points within the treatment weeks in non dropout participants were Missing Completely at Random and so were imputed using multiple regression. A total of 42 out of 532 data points in the kudzu extract group and 26 out of 357 data points in the placebo group were handled this way, corresponding to 7.9% and 7.3% of the data, respectively. Because prescription medications are not universally used or have a perceived modest effect (Krystal et al., 2001; Mark et al., 2003), providing heavy drinkers with any type of intervention that yields even a modest reduction in drinking is desirable. Furthermore, there is a need to develop efficacious medicines from natural products that have a low incidence of side effects or toxicity (Xu et al., 2005). The ultimate role that natural preparations play will be complementary and might be useful in treating drug withdrawal and possibly relapse (Lu et al., 2009).
8 Other Effects
The CPT II was administered on a separate laptop computer in the experimental chamber at 45 and 60 minutes after alcohol administration; after 1 hour, CPT II was administered every 30 minutes until the end of the session at 3 hours. As a result, the researchers gave compounds from Kudzu root to the special lab rats. Anecdotal sources also note that kudzu root may lower blood sugar too much or slow down blood clotting. Nevertheless, it may be a good idea to avoid if you use blood thinning or diabetes medications. Another study found that people who took puerarin, an isoflavone extract from the kudzu plant, prior to drinking took longer to consume alcoholic beverages (3).
Rats
A linear mixed model analysis of variance (SPSS 13.0 for MAC OS X) was performed for dependent variables using the main factors of dose, pretreatment condition, and time, as appropriate. Because of this effect, it might also be helpful for people who have quit drinking and want to make sure that a potential slip doesn’t become a full-blown relapse. Taking this plant would decrease the chance that a drink would turn into an endless parade of drinks. Of course, it’s up to the individual to ensure that he or she doesn’t use this as an excuse to fall off the wagon. Kudzu root may increase the risk of liver injury or interact with certain medications, like birth control. Anecdotal sources say it may also be harmful to take with medications for diabetes or blood clotting.
- Research has found that kudzu can help reduce hot flashes and night sweats, as well as improve sleep quality.
- Sporadic missing data from the actiwatches were filled in from the back up daily diary data.
- This transient effect during the first 30 minutes of the ascending plasma alcohol curve lasted only minutes; there were no differences in peak plasma alcohol levels or alcohol elimination kinetics.
- In conclusion, while kudzu shows promise as a natural remedy for alcoholism, more rigorous clinical studies are needed to determine its effectiveness.
Participants
Over time, chronic alcoholism leads to structural and functional changes in the brain. These changes affect parts of the brain related to emotional regulation, memory, and decision-making. The introduction of kudzu to the United States dates back to the late 19th and early 20th centuries. Initially promoted as a forage crop and an ornamental plant, kudzu was later recognized for its soil erosion control capabilities.
Ultimately, a comprehensive approach to health and well-being, including evidence-based treatments, remains paramount. This is because isoflavones can help dilate blood vessels, allowing for better blood flow. Kudzu may also help reduce the risk of blood clots, which can lead to heart attacks and strokes. Kudzu, also known as Pueraria Montana, is a climbing vine that belongs to the pea family. This invasive weed is native to East Asia, particularly China, Japan, and Korea, where it has been used for centuries in traditional Chinese medicine. Moreover, kudzu might assist with the prevention of relapses by supporting the stabilization of neurotransmitter levels in the brain.
- Until the effects of kudzu can be quantified properly in a larger study, then, and a standardised product is available on the market with the THR mark, it’s not something we can recommend you take.
- It’s never a good idea to combine alcohol with any substance, including herbal supplements.
- All other authors declare that they have no actual or potential conflict of interest that could inappropriately influence, or be perceived to influence, this work.
During the baseline session, the placebo-randomized group consumed 2.7 ± 0.78 beers before treatment and increased consumption to 3.4 ± 1.1 beers after treatment. The kudzu group significantly reduced consumption from 3.0 ± 1.7 at baseline to 1.9 ± 1.3 beers after treatment. The placebo-treated group opened 33 beers during baseline conditions and 38 following treatment whereas the kudzu-treated group opened 32 beers during baseline conditions and only 21 following treatment. Kudzu extracts may interact with GABA receptors and enhance the inhibitory effects of GABA. The modulation of this system could reduce alcohol cravings or help treat alcohol abuse by lowering anxiety levels and stress that are often triggers to drink. Kudzu is an invasive vine that natively grows in East Asia—especially drug addiction treatment China and Japan.